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SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N2CCOC[C@@H]2C)c2COCCn12)c1ccccc1

InChI Key: InChIKey=PNCHLPXENHHJTE-QFBILLFUSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 218523   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium channel subfamily K member 3


(Homo sapiens (Human))		BDBM218523
PNG
(US9284333, 16kh)
Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCOC[C@@H]2C)c2COCCn12)c1ccccc1 |r|
Show InChI InChI=1S/C23H29N3O4/c1-3-19(17-7-5-4-6-8-17)24-22(27)20-13-18(21-15-30-12-10-26(20)21)23(28)25-9-11-29-14-16(25)2/h4-8,13,16,19H,3,9-12,14-15H2,1-2H3,(H,24,27)/t16-,19+/m0/s1
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PC cid
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US Patent
n/an/a 990n/an/an/an/an/a25



Sanofi

US Patent


Assay Description
Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...

US Patent US9284333 (2016)


BindingDB Entry DOI: 10.7270/Q2FJ2FMC
More data for this
Ligand-Target Pair