null

SMILES: CN(C)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1

InChI Key: InChIKey=MYRPEVBCFHHODE-YHYXMXQVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218902 (US9303033, I3, Table 12A, Compound 4) Show SMILES CN(C)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 Show InChI InChI=1S/C15H16N6O2S/c1-20(2)11-6-12(17-9-3-4-9)21-13(18-11)8(7-16-21)5-10-14(22)19-15(23)24-10/h5-7,9,17H,3-4H2,1-2H3,(H,19,22,23)/b10-5-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM218902 (US9303033, I3, Table 12A, Compound 4) Show SMILES CN(C)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 Show InChI InChI=1S/C15H16N6O2S/c1-20(2)11-6-12(17-9-3-4-9)21-13(18-11)8(7-16-21)5-10-14(22)19-15(23)24-10/h5-7,9,17H,3-4H2,1-2H3,(H,19,22,23)/b10-5-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 30 uM ATP: In a final reaction volume of 50 ul, recombinant PIM-1 (1 ng) was incubated with 12 mM MOPS pH 7.0, 0.4 mM EDTA, glycerol 1%, brij 35 0.00...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM218902 (US9303033, I3, Table 12A, Compound 4) Show SMILES CN(C)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 Show InChI InChI=1S/C15H16N6O2S/c1-20(2)11-6-12(17-9-3-4-9)21-13(18-11)8(7-16-21)5-10-14(22)19-15(23)24-10/h5-7,9,17H,3-4H2,1-2H3,(H,19,22,23)/b10-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	876	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair