BDBM218980 US9303033, H6, Table 19A, Compound 7

SMILES: Clc1cccc(Nc2cc(NCc3ccccn3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1

InChI Key: InChIKey=CHEJAVBQMRDDMQ-IUXPMGMMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit beta (CK2 beta) (Homo sapiens (Human))	BDBM218980 (US9303033, H6, Table 19A, Compound 7) Show SMILES Clc1cccc(Nc2cc(NCc3ccccn3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 Show InChI InChI=1S/C22H17ClN8O2/c23-14-4-3-6-15(9-14)27-18-10-19(25-12-16-5-1-2-7-24-16)31-20(29-18)13(11-26-31)8-17-21(32)30-22(33)28-17/h1-11,25H,12H2,(H,27,29)(H2,28,30,32,33)/b17-8-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	421	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218980 (US9303033, H6, Table 19A, Compound 7) Show SMILES Clc1cccc(Nc2cc(NCc3ccccn3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 Show InChI InChI=1S/C22H17ClN8O2/c23-14-4-3-6-15(9-14)27-18-10-19(25-12-16-5-1-2-7-24-16)31-20(29-18)13(11-26-31)8-17-21(32)30-22(33)28-17/h1-11,25H,12H2,(H,27,29)(H2,28,30,32,33)/b17-8-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair