null

SMILES: Cc1ccc(cc1F)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=ZWBGIVRPYAFQIC-CHHVJCJISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220053 (US9303033, W47, Table 58A, Compound 20) Show SMILES Cc1ccc(cc1F)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H18FN7O3/c1-10-2-3-11(6-14(10)22)19(30)27-16-8-17(24-13-4-5-13)29-18(26-16)12(9-23-29)7-15-20(31)28-21(32)25-15/h2-3,6-9,13,24H,4-5H2,1H3,(H,26,27,30)(H2,25,28,31,32)/b15-7-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220053 (US9303033, W47, Table 58A, Compound 20) Show SMILES Cc1ccc(cc1F)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C21H18FN7O3/c1-10-2-3-11(6-14(10)22)19(30)27-16-8-17(24-13-4-5-13)29-18(26-16)12(9-23-29)7-15-20(31)28-21(32)25-15/h2-3,6-9,13,24H,4-5H2,1H3,(H,26,27,30)(H2,25,28,31,32)/b15-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.18E+4	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair