null

SMILES: Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key: InChIKey=KTNMINICNIMBSV-YVNNLAQVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit beta (Homo sapiens (Human))	BDBM220066 (BDBM220085 | US9303033, J48, Table 58A, Compound 3...) Show SMILES Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.73E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220066 (BDBM220085 | US9303033, J48, Table 58A, Compound 3...) Show SMILES Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM220066 (BDBM220085 | US9303033, J48, Table 58A, Compound 3...) Show SMILES Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 Show InChI InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair