BDBM220381 US9290488, ZA02

SMILES: CC(=O)N[C@@H]1CN([C@@H]1C(O)=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@H]2C[C@@H]3C[C@H](C2)CCCC3)c1=O

InChI Key: InChIKey=ZWKGONHGSWYTAN-IWYPPAETSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM220381 (US9290488, ZA02) Show SMILES CC(=O)N[C@@H]1CN([C@@H]1C(O)=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@H]2C[C@@H]3C[C@H](C2)CCCC3)c1=O |r,THB:29:28:20.21.27:23.25.24| Show InChI InChI=1S/C32H43N5O4/c1-19(38)33-27-18-35(29(27)32(40)41)30-31(39)37(28-12-5-4-11-26(28)34-30)25-16-22-9-6-10-23(17-25)36(22)24-14-20-7-2-3-8-21(13-20)15-24/h4-5,11-12,20-25,27,29H,2-3,6-10,13-18H2,1H3,(H,33,38)(H,40,41)/t20-,21+,22-,23+,24-,25+,27-,29+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.14	-11.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in a ...				US Patent US9290488 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SCW
					More data for this Ligand-Target Pair
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM220381 (US9290488, ZA02) Show SMILES CC(=O)N[C@@H]1CN([C@@H]1C(O)=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3[C@H]2C[C@@H]3C[C@H](C2)CCCC3)c1=O |r,THB:29:28:20.21.27:23.25.24| Show InChI InChI=1S/C32H43N5O4/c1-19(38)33-27-18-35(29(27)32(40)41)30-31(39)37(28-12-5-4-11-26(28)34-30)25-16-22-9-6-10-23(17-25)36(22)24-14-20-7-2-3-8-21(13-20)15-24/h4-5,11-12,20-25,27,29H,2-3,6-10,13-18H2,1H3,(H,33,38)(H,40,41)/t20-,21+,22-,23+,24-,25+,27-,29+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24.2	n/a	n/a	7.4	25
Purdue Pharma L.P. US Patent					Assay Description ORL-1 membrane solution was prepared by sequentially adding final concentrations of 0.066 μg/μL ORL-1 membrane protein, 10 μg/mL saponin, 3 ...				US Patent US9290488 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SCW
					More data for this Ligand-Target Pair