BDBM220398 US9296708, 4, ARM-P4
SMILES: OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCn1cc(COCCOCCOCCOCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)nn1)C(O)=O)C(O)=O
InChI Key: InChIKey=OZXNUTGMCCPZLB-ZEQRLZLVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human)) | BDBM220398 (US9296708, 4, ARM-P4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
YALE UNIVERSITY US Patent | Assay Description For IC50 measurements, inhibitors were dissolved in Reaction Buffer containing 40 μM NAAG to a final volume of 100 μL. Then, 25 μL of this s... | US Patent US9296708 (2016) BindingDB Entry DOI: 10.7270/Q2BP01P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase II (Homo sapiens (Human)) | BDBM220398 (US9296708, 4, ARM-P4) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
McMaster University Curated by ChEMBL | Assay Description Displacement of [125I]23 from PSMA in human LNCAP cells | J Med Chem 59: 2660-73 (2016) BindingDB Entry DOI: 10.7270/Q2X068XP | |||||||||||
More data for this Ligand-Target Pair |