BDBM220864 US9302986, 8
SMILES: CN(C)C(=O)c1ccc(SCC(CN)=CF)cc1
InChI Key: InChIKey=PEKJZDMDQTYGPU-JXMROGBWSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM220864 (US9302986, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | n/a |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM220864 (US9302986, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair |