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SMILES: Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1ncc([nH]1)C1(CCC1)C(F)(F)F

InChI Key: InChIKey=NFVXETNKZFAUNY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 220926   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM220926
PNG
(US9302996, 41)
Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(cc1)-c1ncc([nH]1)C1(CCC1)C(F)(F)F
Show InChI InChI=1S/C25H26F3N3O3/c1-15-11-20(34-14-23(2,3)22(32)33)29-12-18(15)16-5-7-17(8-6-16)21-30-13-19(31-21)24(9-4-10-24)25(26,27)28/h5-8,11-13H,4,9-10,14H2,1-3H3,(H,30,31)(H,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/a7.430



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...

US Patent US9302996 (2016)


BindingDB Entry DOI: 10.7270/Q2TM790N
More data for this
Ligand-Target Pair