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SMILES: CCC(CC)(COc1cc(C)c(cn1)-c1ccc(nc1)-c1ncc([nH]1)C(F)(F)F)C(O)=O

InChI Key: InChIKey=MAKJJSLTZKBKHX-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221012   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM221012
PNG
(US9302996, 127)
Show SMILES CCC(CC)(COc1cc(C)c(cn1)-c1ccc(nc1)-c1ncc([nH]1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H23F3N4O3/c1-4-21(5-2,20(30)31)12-32-18-8-13(3)15(10-27-18)14-6-7-16(26-9-14)19-28-11-17(29-19)22(23,24)25/h6-11H,4-5,12H2,1-3H3,(H,28,29)(H,30,31)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/a7.430



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...

US Patent US9302996 (2016)


BindingDB Entry DOI: 10.7270/Q2TM790N
More data for this
Ligand-Target Pair