BDBM221122 US9303012, 48

SMILES: CC1(C)COCN1C(=O)c1ccc(OC(F)(F)F)c(OCC2CC2)n1

InChI Key: InChIKey=WEBQDSSOWLKLLA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 221122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM221122 (US9303012, 48) Show SMILES CC1(C)COCN1C(=O)c1ccc(OC(F)(F)F)c(OCC2CC2)n1 Show InChI InChI=1S/C16H19F3N2O4/c1-15(2)8-23-9-21(15)14(22)11-5-6-12(25-16(17,18)19)13(20-11)24-7-10-3-4-10/h5-6,10H,3-4,7-9H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM221122 (US9303012, 48) Show SMILES CC1(C)COCN1C(=O)c1ccc(OC(F)(F)F)c(OCC2CC2)n1 Show InChI InChI=1S/C16H19F3N2O4/c1-15(2)8-23-9-21(15)14(22)11-5-6-12(25-16(17,18)19)13(20-11)24-7-10-3-4-10/h5-6,10H,3-4,7-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	108	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair