BDBM221307 US9303023, 6

SMILES: Cc1ccc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)nc1

InChI Key: InChIKey=JMCZUXKBUQBLNN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM221307 (US9303023, 6) Show SMILES Cc1ccc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)nc1 Show InChI InChI=1S/C22H22N6O2/c1-15-4-3-5-17(10-15)21-20(25-14-30-21)22(29)27-18-12-26-28(13-18)9-8-23-19-7-6-16(2)11-24-19/h3-7,10-14H,8-9H2,1-2H3,(H,23,24)(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10
					More data for this Ligand-Target Pair