BDBM221409 US9303023, 106

SMILES: Cc1cccc(c1)-c1ocnc1C(=O)Nc1cnn(CCn2ccc3cc(Cl)c(Cl)cc23)c1

InChI Key: InChIKey=XVHHLHAYRHOBBF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM221409 (US9303023, 106) Show SMILES Cc1cccc(c1)-c1ocnc1C(=O)Nc1cnn(CCn2ccc3cc(Cl)c(Cl)cc23)c1 Show InChI InChI=1S/C24H19Cl2N5O2/c1-15-3-2-4-17(9-15)23-22(27-14-33-23)24(32)29-18-12-28-31(13-18)8-7-30-6-5-16-10-19(25)20(26)11-21(16)30/h2-6,9-14H,7-8H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...				US Patent US9303023 (2016) BindingDB Entry DOI: 10.7270/Q2251H10
					More data for this Ligand-Target Pair