BDBM221601 US9303045, 88::US9695195, 88
SMILES: CN1C2CCCC1CC(C2)OC(=O)c1c(C)n(CCF)c2ccccc12
InChI Key: InChIKey=PAFKEMDUIAFUOD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM221601 (US9303045, 88 | US9695195, 88) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a... | US Patent US9695195 (2017) BindingDB Entry DOI: 10.7270/Q28050RV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 3A (Homo sapiens (Human)) | BDBM221601 (US9303045, 88 | US9695195, 88) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The 5HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux a... | US Patent US9303045 (2016) BindingDB Entry DOI: 10.7270/Q2NZ86HD | |||||||||||
More data for this Ligand-Target Pair |