BDBM221981 US9303035, 5.1
SMILES: C[C@@H]1COC(c2nc(C)cs2)c2n1c(-c1ccccc1)c1c2n(C)c(=O)n(C)c1=O
InChI Key: InChIKey=WKCKYLFWKOJBAQ-BSOCMFCZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cystic fibrosis transmembrane conductance regulator protein (CFTR) (Cricetulus griseus (Chinese hamster)) | BDBM221981 (US9303035, 5.1) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.24 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair |