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SMILES: COc1ccc2N(Cc3cn(Cc4ccc(cc4)C(=O)NO)nn3)C(=O)\C(=N/O)c2c1

InChI Key: InChIKey=YPMMXKMDKYIXSY-PYCFMQQDSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222228   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 2


(Homo sapiens (Human))		BDBM222228
PNG
(N-Hydroxy-4-((4-((3-(hydroxyimino)-5-methoxy-2-oxo...)
Show SMILES COc1ccc2N(Cc3cn(Cc4ccc(cc4)C(=O)NO)nn3)C(=O)\C(=N/O)c2c1
Show InChI InChI=1S/C20H18N6O5/c1-31-15-6-7-17-16(8-15)18(22-29)20(28)26(17)11-14-10-25(24-21-14)9-12-2-4-13(5-3-12)19(27)23-30/h2-8,10,29-30H,9,11H2,1H3,(H,23,27)/b22-18-
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.92E+3n/an/an/an/an/an/a



Hanoi University of Pharmacy



Assay Description
The HDAC enzymatic assay was performed using a Fluorogenic HDAC Assay Kit (BPS Bioscience) according to the manufacturer's instructions. Briefly,...

Bioorg Chem 71: 160-169 (2017)


Article DOI: 10.1016/j.bioorg.2017.02.002
BindingDB Entry DOI: 10.7270/Q2TH8KJG
More data for this
Ligand-Target Pair