BDBM222674 US9315493, 6

SMILES: CCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=RYHZXBYVUVJCGO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PPARgamma2 - DNA binding domain of Gal4 (Saccharomyces bayanus (Yeast)-Homo sapiens (Human))	BDBM222674 (US9315493, 6) Show SMILES CCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H33N9O2/c1-5-7-12-26-24(29(40)39(28(34-26)19(3)4)30-32-17-21(18-33-30)41-6-2)15-20-13-14-25(31-16-20)22-10-8-9-11-23(22)27-35-37-38-36-27/h8-11,13-14,16-19H,5-7,12,15H2,1-4H3,(H,35,36,37,38)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a
KOWA COMPANY, LTD. US Patent					Assay Description As an expression vector, a chimera in which DNA binding domain of Gal4, which is a yeast transcription factor, and ligand binding domain of human PPA...				US Patent US9315493 (2016) BindingDB Entry DOI: 10.7270/Q27M06SS
					More data for this Ligand-Target Pair