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BDBM222685 US9315493, 17

SMILES: CCCCc1nc(C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=UAYJOWRHQDDLOC-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PPARgamma2 - DNA binding domain of Gal4


(Saccharomyces bayanus (Yeast)-Homo sapiens (Human))
BDBM222685
PNG
(US9315493, 17)
Show SMILES CCCCc1nc(C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1
Show InChI InChI=1S/C29H29N7O4/c1-4-6-11-25-23(27(37)36(18(3)33-25)28-31-16-20(17-32-28)39-5-2)14-19-12-13-24(30-15-19)21-9-7-8-10-22(21)26-34-29(38)40-35-26/h7-10,12-13,15-17H,4-6,11,14H2,1-3H3,(H,34,35,38)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 3.12E+3n/an/an/an/a



KOWA COMPANY, LTD.

US Patent


Assay Description
As an expression vector, a chimera in which DNA binding domain of Gal4, which is a yeast transcription factor, and ligand binding domain of human PPA...


US Patent US9315493 (2016)


BindingDB Entry DOI: 10.7270/Q27M06SS
More data for this
Ligand-Target Pair