BDBM222686 US9315493, 18

SMILES: CCCCc1nc(CC)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=VSBSEYGNUXPJGW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma [182-505]/Regulatory protein GAL4 [1-147] (Saccharomyces bayanus (Yeast)-Homo sapiens (Human))	BDBM222686 (US9315493, 18) Show SMILES CCCCc1nc(CC)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1 Show InChI InChI=1S/C29H29N7O4/c1-4-6-11-24-22(27(37)36(25(5-2)33-24)28-31-16-19(39-3)17-32-28)14-18-12-13-23(30-15-18)20-9-7-8-10-21(20)26-34-29(38)40-35-26/h7-10,12-13,15-17H,4-6,11,14H2,1-3H3,(H,34,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a
KOWA COMPANY, LTD. US Patent					Assay Description As an expression vector, a chimera in which DNA binding domain of Gal4, which is a yeast transcription factor, and ligand binding domain of human PPA...				US Patent US9315493 (2016) BindingDB Entry DOI: 10.7270/Q27M06SS
					More data for this Ligand-Target Pair