BDBM222690 US9315493, 22

SMILES: CCCCc1nc(C2CC2)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=RCQUGTAGHGPUFH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PPARgamma2 - DNA binding domain of Gal4 (Saccharomyces bayanus (Yeast)-Homo sapiens (Human))	BDBM222690 (US9315493, 22) Show SMILES CCCCc1nc(C2CC2)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1 Show InChI InChI=1S/C30H29N7O4/c1-3-4-9-25-23(28(38)37(27(34-25)19-11-12-19)29-32-16-20(40-2)17-33-29)14-18-10-13-24(31-15-18)21-7-5-6-8-22(21)26-35-30(39)41-36-26/h5-8,10,13,15-17,19H,3-4,9,11-12,14H2,1-2H3,(H,35,36,39)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a
KOWA COMPANY, LTD. US Patent					Assay Description As an expression vector, a chimera in which DNA binding domain of Gal4, which is a yeast transcription factor, and ligand binding domain of human PPA...				US Patent US9315493 (2016) BindingDB Entry DOI: 10.7270/Q27M06SS
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