BDBM222710 US9315493, 42

SMILES: CCCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1

InChI Key: InChIKey=KKDVUJRGMGHAOG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PPARgamma2 - DNA binding domain of Gal4 (Saccharomyces bayanus (Yeast)-Homo sapiens (Human))	BDBM222710 (US9315493, 42) Show SMILES CCCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(nc1)-c1ccccc1-c1noc(=O)[nH]1 Show InChI InChI=1S/C32H35N7O4/c1-5-7-8-13-27-25(30(40)39(29(36-27)20(3)4)31-34-18-22(19-35-31)42-6-2)16-21-14-15-26(33-17-21)23-11-9-10-12-24(23)28-37-32(41)43-38-28/h9-12,14-15,17-20H,5-8,13,16H2,1-4H3,(H,37,38,41)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
KOWA COMPANY, LTD. US Patent					Assay Description As an expression vector, a chimera in which DNA binding domain of Gal4, which is a yeast transcription factor, and ligand binding domain of human PPA...				US Patent US9315493 (2016) BindingDB Entry DOI: 10.7270/Q27M06SS
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