BDBM222903 US9315499, 3038

SMILES: CC1(C)CN(C1)C(=O)Cn1c2nccc(OC[C@@H]3CCC(=O)N3)c2cc(C(=O)NCc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=HKPRIXZNIVOGOP-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222903 (US9315499, 3038) Show SMILES CC1(C)CN(C1)C(=O)Cn1c2nccc(OC[C@@H]3CCC(=O)N3)c2cc(C(=O)NCc2ccc(Cl)cc2)c1=O |r| Show InChI InChI=1S/C28H30ClN5O5/c1-28(2)15-33(16-28)24(36)13-34-25-20(22(9-10-30-25)39-14-19-7-8-23(35)32-19)11-21(27(34)38)26(37)31-12-17-3-5-18(29)6-4-17/h3-6,9-11,19H,7-8,12-16H2,1-2H3,(H,31,37)(H,32,35)/t19-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair