BDBM222910 US9315499, 4024

SMILES: CC1(C)CN(C1)C(=O)Cn1c2ncc(CN3CCNC(C3)C(F)(F)F)cc2cc(C(=O)NCc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=XRUCFBFUMPJGAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222910 (US9315499, 4024) Show SMILES CC1(C)CN(C1)C(=O)Cn1c2ncc(CN3CCNC(C3)C(F)(F)F)cc2cc(C(=O)NCc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C29H32ClF3N6O3/c1-28(2)16-38(17-28)24(40)15-39-25-20(9-19(12-35-25)13-37-8-7-34-23(14-37)29(31,32)33)10-22(27(39)42)26(41)36-11-18-3-5-21(30)6-4-18/h3-6,9-10,12,23,34H,7-8,11,13-17H2,1-2H3,(H,36,41)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	74	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair