BDBM222916 US9315499, 4065

SMILES: COc1cc(CNC(=O)c2cc3cc(cnc3n(CC(=O)N3CC(C)(F)C3)c2=O)-c2cn(C)cn2)ccc1Cl

InChI Key: InChIKey=AJQMPZJMJZMTMR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222916 (US9315499, 4065) Show SMILES COc1cc(CNC(=O)c2cc3cc(cnc3n(CC(=O)N3CC(C)(F)C3)c2=O)-c2cn(C)cn2)ccc1Cl Show InChI InChI=1S/C27H26ClFN6O4/c1-27(29)13-34(14-27)23(36)12-35-24-17(7-18(10-30-24)21-11-33(2)15-32-21)8-19(26(35)38)25(37)31-9-16-4-5-20(28)22(6-16)39-3/h4-8,10-11,15H,9,12-14H2,1-3H3,(H,31,37)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair