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SMILES: Cc1c[nH]c2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cc4cn[nH]c(=O)c34)cc(F)cc12

InChI Key: InChIKey=VNEFLTJAFNLKGA-JKSUJKDBSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222934   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK [2-635]


(Homo sapiens (Human))		BDBM222934
PNG
(US9315500, 2.4)
Show SMILES Cc1c[nH]c2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cc4cn[nH]c(=O)c34)cc(F)cc12
Show InChI InChI=1S/C22H24FN7O/c1-11-9-25-20-14(11)7-13(23)8-17(20)28-21-19-12(10-26-30-22(19)31)6-18(29-21)27-16-5-3-2-4-15(16)24/h6-10,15-16,25H,2-5,24H2,1H3,(H,30,31)(H2,27,28,29)/t15-,16+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.30n/an/an/an/a7.530



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...

US Patent US9315500 (2016)


BindingDB Entry DOI: 10.7270/Q2V986WN
More data for this
Ligand-Target Pair