BDBM22303 N-{3-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]propyl}-4-pentylbenzene-1-sulfonamide::homotryptamine sulfonamide, 37m

SMILES: CCCCCc1ccc(cc1)S(=O)(=O)NCCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1

InChI Key: InChIKey=NIXVPRZGLWPRBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Oryctolagus cuniculus (rabbit))	BDBM22303 (N-{3-[2-(1-benzofuran-2-yl)-1H-indol-3-yl]propyl}-...) Show SMILES CCCCCc1ccc(cc1)S(=O)(=O)NCCCc1c([nH]c2ccccc12)-c1cc2ccccc2o1 Show InChI InChI=1S/C30H32N2O3S/c1-2-3-4-10-22-16-18-24(19-17-22)36(33,34)31-20-9-13-26-25-12-6-7-14-27(25)32-30(26)29-21-23-11-5-8-15-28(23)35-29/h5-8,11-12,14-19,21,31-32H,2-4,9-10,13,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...				Bioorg Med Chem Lett 15: 1435-40 (2005) Article DOI: 10.1016/j.bmcl.2004.12.081 BindingDB Entry DOI: 10.7270/Q2T43RD2
					More data for this Ligand-Target Pair