null
SMILES: CCN(C(=O)Cn1c(cc2sccc12)C(=O)N[C@H]1CC[C@@H](CC1)C(=O)OC)c1cccc(CC)c1
InChI Key: InChIKey=NVGBNVFQDQGXIH-MXVIHJGJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oplophorus-luciferin 2-monooxygenase catalytic subunit (Oplophorus gracilirostris (Luminous shrimp)) | BDBM223160 (Methyl trans-4-(4-(2-(ethyl(3-ethylphenyl)amino)-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Promega Biosciences LLC | Assay Description NanoLuc enzyme was diluted to 0.4 ng/mL in CO2 independent media + 10% FBS to make the detection reagent. A 3× dilution series of each inhibitor was ... | ACS Chem Biol 12: 1028-1037 (2017) Article DOI: 10.1021/acschembio.6b01129 BindingDB Entry DOI: 10.7270/Q2SF2V1S | |||||||||||
More data for this Ligand-Target Pair |