BDBM22335 (5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiazol-2-ylamino)-4,5-dihydro-1,3-thiazol-4-one::thiazolidinone derivative, 1

SMILES: Oc1ccc(C=C2SC(Nc3nccs3)=NC2=O)cc1

InChI Key: InChIKey=OLCHTIJXNVKOCF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM22335 ((5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiaz...) Show SMILES Oc1ccc(C=C2SC(Nc3nccs3)=NC2=O)cc1 |w:5.4,c:15| Show InChI InChI=1S/C13H9N3O2S2/c17-9-3-1-8(2-4-9)7-10-11(18)15-13(20-10)16-12-14-5-6-19-12/h1-7,17H,(H,14,15,16,18)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	8.0	37
Aristotle University					Assay Description The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...				J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ
					More data for this Ligand-Target Pair
Lipoxygenase-1 (Glycine max (soybean))	BDBM22335 ((5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiaz...) Show SMILES Oc1ccc(C=C2SC(Nc3nccs3)=NC2=O)cc1 |w:5.4,c:15| Show InChI InChI=1S/C13H9N3O2S2/c17-9-3-1-8(2-4-9)7-10-11(18)15-13(20-10)16-12-14-5-6-19-12/h1-7,17H,(H,14,15,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	7.4	28
Aristotle University					Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ...				J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ
					More data for this Ligand-Target Pair