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SMILES: COc1cc(OCc2ccccn2)ccc1\C=C\c1cc(\C=C\c2ccnn2C)[nH]n1

InChI Key: InChIKey=AUHOWEZDFIXGHY-QGHYKFKQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223583   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM223583
PNG
(US9321752, 42-2)
Show SMILES COc1cc(OCc2ccccn2)ccc1\C=C\c1cc(\C=C\c2ccnn2C)[nH]n1
Show InChI InChI=1S/C24H23N5O2/c1-29-22(12-14-26-29)10-9-20-15-19(27-28-20)8-6-18-7-11-23(16-24(18)30-2)31-17-21-5-3-4-13-25-21/h3-16H,17H2,1-2H3,(H,27,28)/b8-6+,10-9+
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 830n/an/an/an/a7.6n/a



GREEN TECH CO., LTD.

US Patent


Assay Description
Recombinant three-repeat microtubule-binding domain (3R-MBD) of tau protein was expressed in E. coli and was purified and used for the experiment. Th...

US Patent US9321752 (2016)


BindingDB Entry DOI: 10.7270/Q2T72G92
More data for this
Ligand-Target Pair