BDBM2236 2-Pyridinone derivative 16::3-[2-(4-Fluorobenzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one::5-ethyl-3-[2-(4-fluoro-1,3-benzoxazol-2-yl)ethyl]-6-methyl-1,2-dihydropyridin-2-one::CHEMBL176362

SMILES: CCc1cc(CCc2nc3c(F)cccc3o2)c(=O)[nH]c1C

InChI Key: InChIKey=PHPHYTVUIHUSDY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM2236 (2-Pyridinone derivative 16 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM2236 (2-Pyridinone derivative 16 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair