BDBM22442 Acyl Hydrazone, 7::N'-[(1E)-[4-(diethylamino)phenyl]methylidene]benzohydrazide
SMILES: CCN(CC)c1ccc(\C=N\NC(=O)c2ccccc2)cc1
InChI Key: InChIKey=HBZQDULNYRWEEB-XMHGGMMESA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen-Related Receptor, gamma (Homo sapiens (Human)) | BDBM22442 (Acyl Hydrazone, 7 | N'-[(1E)-[4-(diethylamino)phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | 7.0 | 22 |
GSK | Assay Description Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra... | J Med Chem 48: 3107-9 (2005) Article DOI: 10.1021/jm050161j BindingDB Entry DOI: 10.7270/Q2S46Q77 | |||||||||||
More data for this Ligand-Target Pair |