BDBM22443 4-amino-N'-[(1E)-[4-(diethylamino)phenyl]methylidene]benzohydrazide::Acyl Hydrazone, 8

SMILES: CCN(CC)c1ccc(\C=N\NC(=O)c2ccc(N)cc2)cc1

InChI Key: InChIKey=WBNPZDJIFBDPOL-DEDYPNTBSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen-Related Receptor, gamma (Homo sapiens (Human))	BDBM22443 (4-amino-N'-[(1E)-[4-(diethylamino)phenyl]methylide...) Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)c2ccc(N)cc2)cc1 Show InChI InChI=1S/C18H22N4O/c1-3-22(4-2)17-11-5-14(6-12-17)13-20-21-18(23)15-7-9-16(19)10-8-15/h5-13H,3-4,19H2,1-2H3,(H,21,23)/b20-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	7.0	22
GSK					Assay Description Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra...				J Med Chem 48: 3107-9 (2005) Article DOI: 10.1021/jm050161j BindingDB Entry DOI: 10.7270/Q2S46Q77
					More data for this Ligand-Target Pair