BDBM22445 Acyl Hydrazone, 10::N'-[(1E)-1-[4-(diethylamino)phenyl]ethylidene]-4-hydroxybenzohydrazide

SMILES: CCN(CC)c1ccc(cc1)C(C)=NNC(=O)c1ccc(O)cc1

InChI Key: InChIKey=CCIJBOQESPRHPT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen-Related Receptor, gamma (Homo sapiens (Human))	BDBM22445 (Acyl Hydrazone, 10 | N'-[(1E)-1-[4-(diethylamino)p...) Show SMILES CCN(CC)c1ccc(cc1)C(C)=NNC(=O)c1ccc(O)cc1 |w:13.14| Show InChI InChI=1S/C19H23N3O2/c1-4-22(5-2)17-10-6-15(7-11-17)14(3)20-21-19(24)16-8-12-18(23)13-9-16/h6-13,23H,4-5H2,1-3H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	7.0	22
GSK					Assay Description Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra...				J Med Chem 48: 3107-9 (2005) Article DOI: 10.1021/jm050161j BindingDB Entry DOI: 10.7270/Q2S46Q77
					More data for this Ligand-Target Pair