BDBM224573 US10202383, Example 2(3)::US9321791, 2(3)::US9556175, 2(3)

SMILES: [#6]-[#6](-[#6](=O)-c1ccccc1)-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O

InChI Key: InChIKey=NGHCPUTUXDWBEH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224573 (US10202383, Example 2(3) | US9321791, 2(3) | US955...) Show SMILES [#6]-[#6](-[#6](=O)-c1ccccc1)-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C25H32N6O3/c1-16(2)12-14-30-20-22(27-24(30)29-13-8-11-19(26)15-29)28(4)25(34)31(23(20)33)17(3)21(32)18-9-6-5-7-10-18/h5-7,9-10,12,17,19H,8,11,13-15,26H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224573 (US10202383, Example 2(3) | US9321791, 2(3) | US955...) Show SMILES [#6]-[#6](-[#6](=O)-c1ccccc1)-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C25H32N6O3/c1-16(2)12-14-30-20-22(27-24(30)29-13-8-11-19(26)15-29)28(4)25(34)31(23(20)33)17(3)21(32)18-9-6-5-7-10-18/h5-7,9-10,12,17,19H,8,11,13-15,26H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224573 (US10202383, Example 2(3) | US9321791, 2(3) | US955...) Show SMILES [#6]-[#6](-[#6](=O)-c1ccccc1)-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C25H32N6O3/c1-16(2)12-14-30-20-22(27-24(30)29-13-8-11-19(26)15-29)28(4)25(34)31(23(20)33)17(3)21(32)18-9-6-5-7-10-18/h5-7,9-10,12,17,19H,8,11,13-15,26H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair