BDBM224580 US10202383, Example 2(35)::US9321791, 2(35)::US9556175, 2(35)

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-n1c(nc2n(-[#6])c(=O)n(-[#6]-[#6](=O)-c3cccc(c3)-[#6](-[#8])=O)c(=O)c12)-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-1

InChI Key: InChIKey=QUTIPHIQWJGVAT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224580 (US10202383, Example 2(35) | US9321791, 2(35) | US9...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1c(nc2n(-[#6])c(=O)n(-[#6]-[#6](=O)-c3cccc(c3)-[#6](-[#8])=O)c(=O)c12)-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-1 Show InChI InChI=1S/C25H30N6O5/c1-15(2)9-11-30-20-21(27-24(30)29-10-5-8-18(26)13-29)28(3)25(36)31(22(20)33)14-19(32)16-6-4-7-17(12-16)23(34)35/h4,6-7,9,12,18H,5,8,10-11,13-14,26H2,1-3H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224580 (US10202383, Example 2(35) | US9321791, 2(35) | US9...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1c(nc2n(-[#6])c(=O)n(-[#6]-[#6](=O)-c3cccc(c3)-[#6](-[#8])=O)c(=O)c12)-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-1 Show InChI InChI=1S/C25H30N6O5/c1-15(2)9-11-30-20-21(27-24(30)29-10-5-8-18(26)13-29)28(3)25(36)31(22(20)33)14-19(32)16-6-4-7-17(12-16)23(34)35/h4,6-7,9,12,18H,5,8,10-11,13-14,26H2,1-3H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224580 (US10202383, Example 2(35) | US9321791, 2(35) | US9...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1c(nc2n(-[#6])c(=O)n(-[#6]-[#6](=O)-c3cccc(c3)-[#6](-[#8])=O)c(=O)c12)-[#7]-1-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-1 Show InChI InChI=1S/C25H30N6O5/c1-15(2)9-11-30-20-21(27-24(30)29-10-5-8-18(26)13-29)28(3)25(36)31(22(20)33)14-19(32)16-6-4-7-17(12-16)23(34)35/h4,6-7,9,12,18H,5,8,10-11,13-14,26H2,1-3H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair