BDBM224581 US10202383, Example 2(37)::US9321791, 2(37)::US9556175, 2(37)

SMILES: [#6]-[#7]-[#6](=O)-c1cccc(c1)-[#6](=O)-[#6]-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O

InChI Key: InChIKey=RPGBTRWSSFXHAP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224581 (US10202383, Example 2(37) | US9321791, 2(37) | US9...) Show SMILES [#6]-[#7]-[#6](=O)-c1cccc(c1)-[#6](=O)-[#6]-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C26H33N7O4/c1-16(2)10-12-32-21-22(29-25(32)31-11-6-9-19(27)14-31)30(4)26(37)33(24(21)36)15-20(34)17-7-5-8-18(13-17)23(35)28-3/h5,7-8,10,13,19H,6,9,11-12,14-15,27H2,1-4H3,(H,28,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224581 (US10202383, Example 2(37) | US9321791, 2(37) | US9...) Show SMILES [#6]-[#7]-[#6](=O)-c1cccc(c1)-[#6](=O)-[#6]-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C26H33N7O4/c1-16(2)10-12-32-21-22(29-25(32)31-11-6-9-19(27)14-31)30(4)26(37)33(24(21)36)15-20(34)17-7-5-8-18(13-17)23(35)28-3/h5,7-8,10,13,19H,6,9,11-12,14-15,27H2,1-4H3,(H,28,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224581 (US10202383, Example 2(37) | US9321791, 2(37) | US9...) Show SMILES [#6]-[#7]-[#6](=O)-c1cccc(c1)-[#6](=O)-[#6]-n1c(=O)n(-[#6])c2nc(-[#7]-3-[#6]-[#6]-[#6]-[#6](-[#7])-[#6]-3)n(-[#6]\[#6]=[#6](\[#6])-[#6])c2c1=O Show InChI InChI=1S/C26H33N7O4/c1-16(2)10-12-32-21-22(29-25(32)31-11-6-9-19(27)14-31)30(4)26(37)33(24(21)36)15-20(34)17-7-5-8-18(13-17)23(35)28-3/h5,7-8,10,13,19H,6,9,11-12,14-15,27H2,1-4H3,(H,28,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair