BDBM224614 US10202383, Example 2(287)::US9321791, 2(287)::US9556175, 2(287)

SMILES: Cc1cc2ccccc2c(Cn2c(=O)n(C)c3nc(N4CCC[C@@H](N)C4)n(Cc4ccccc4Cl)c3c2=O)n1

InChI Key: InChIKey=XQRAKJMIYNYGNH-OAQYLSRUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224614 (US10202383, Example 2(287) | US9321791, 2(287) | U...) Show SMILES Cc1cc2ccccc2c(Cn2c(=O)n(C)c3nc(N4CCC[C@@H](N)C4)n(Cc4ccccc4Cl)c3c2=O)n1 Show InChI InChI=1S/C29H30ClN7O2/c1-18-14-19-8-3-5-11-22(19)24(32-18)17-37-27(38)25-26(34(2)29(37)39)33-28(35-13-7-10-21(31)16-35)36(25)15-20-9-4-6-12-23(20)30/h3-6,8-9,11-12,14,21H,7,10,13,15-17,31H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...				US Patent US9321791 (2016) BindingDB Entry DOI: 10.7270/Q2GQ6WNR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224614 (US10202383, Example 2(287) | US9321791, 2(287) | U...) Show SMILES Cc1cc2ccccc2c(Cn2c(=O)n(C)c3nc(N4CCC[C@@H](N)C4)n(Cc4ccccc4Cl)c3c2=O)n1 Show InChI InChI=1S/C29H30ClN7O2/c1-18-14-19-8-3-5-11-22(19)24(32-18)17-37-27(38)25-26(34(2)29(37)39)33-28(35-13-7-10-21(31)16-35)36(25)15-20-9-4-6-12-23(20)30/h3-6,8-9,11-12,14,21H,7,10,13,15-17,31H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US10202383 (2019) BindingDB Entry DOI: 10.7270/Q2P55QNN
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM224614 (US10202383, Example 2(287) | US9321791, 2(287) | U...) Show SMILES Cc1cc2ccccc2c(Cn2c(=O)n(C)c3nc(N4CCC[C@@H](N)C4)n(Cc4ccccc4Cl)c3c2=O)n1 Show InChI InChI=1S/C29H30ClN7O2/c1-18-14-19-8-3-5-11-22(19)24(32-18)17-37-27(38)25-26(34(2)29(37)39)33-28(35-13-7-10-21(31)16-35)36(25)15-20-9-4-6-12-23(20)30/h3-6,8-9,11-12,14,21H,7,10,13,15-17,31H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.8	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description 50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....				US Patent US9556175 (2017) BindingDB Entry DOI: 10.7270/Q2Z03B5T
					More data for this Ligand-Target Pair