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SMILES: COc1cncc(c1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1

InChI Key: InChIKey=FMJPDZXMKIOBKX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM224939 (US9321756, 199) Show SMILES COc1cncc(c1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C16H13N5OS/c1-22-11-4-10(6-18-7-11)13-8-19-14-3-2-9(5-12(13)14)15-20-21-16(17)23-15/h2-8,19H,1H3,(H2,17,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM224939 (US9321756, 199) Show SMILES COc1cncc(c1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C16H13N5OS/c1-22-11-4-10(6-18-7-11)13-8-19-14-3-2-9(5-12(13)14)15-20-21-16(17)23-15/h2-8,19H,1H3,(H2,17,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	618	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM224939 (US9321756, 199) Show SMILES COc1cncc(c1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C16H13N5OS/c1-22-11-4-10(6-18-7-11)13-8-19-14-3-2-9(5-12(13)14)15-20-21-16(17)23-15/h2-8,19H,1H3,(H2,17,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair