BDBM225276 2-[4-(4-Benzylpiperazin-1-yl)phenyl]-1H-benzo[d]imidazole (3d)

SMILES: C(N1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1)c1ccccc1

InChI Key: InChIKey=DAAKUAAOMGJRIE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM225276 (2-[4-(4-Benzylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) Show SMILES C(N1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1)c1ccccc1 Show InChI InChI=1S/C24H24N4/c1-2-6-19(7-3-1)18-27-14-16-28(17-15-27)21-12-10-20(11-13-21)24-25-22-8-4-5-9-23(22)26-24/h1-13H,14-18H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	9.72E+4	n/a	n/a	n/a	n/a	8.0	25
Hacettepe University					Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...				Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK
					More data for this Ligand-Target Pair
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM225276 (2-[4-(4-Benzylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) Show SMILES C(N1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1)c1ccccc1 Show InChI InChI=1S/C24H24N4/c1-2-6-19(7-3-1)18-27-14-16-28(17-15-27)21-12-10-20(11-13-21)24-25-22-8-4-5-9-23(22)26-24/h1-13H,14-18H2,(H,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	5.22E+3	n/a	n/a	n/a	n/a	8.0	25
Hacettepe University					Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...				Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK
					More data for this Ligand-Target Pair