BDBM225290 1,1''-Dipropyl-[3,3':3',3''-terindolin]-2'-one (4k)

SMILES: CCCn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CCC)c2ccccc12

InChI Key: InChIKey=JWQYTHRXSUSMKU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM225290 (1,1''-Dipropyl-[3,3':3',3''...) Show SMILES CCCn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CCC)c2ccccc12 Show InChI InChI=1S/C30H29N3O/c1-3-17-32-19-24(21-11-5-9-15-27(21)32)30(23-13-7-8-14-26(23)31-29(30)34)25-20-33(18-4-2)28-16-10-6-12-22(25)28/h5-16,19-20H,3-4,17-18H2,1-2H3,(H,31,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...				Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025
					More data for this Ligand-Target Pair
alpha-Glucosidase (alpha-Glu) (Saccharomyces cerevisiae)	BDBM225290 (1,1''-Dipropyl-[3,3':3',3''...) Show SMILES CCCn1cc(c2ccccc12)C1(C(=O)Nc2ccccc12)c1cn(CCC)c2ccccc12 Show InChI InChI=1S/C30H29N3O/c1-3-17-32-19-24(21-11-5-9-15-27(21)32)30(23-13-7-8-14-26(23)31-29(30)34)25-20-33(18-4-2)28-16-10-6-12-22(25)28/h5-16,19-20H,3-4,17-18H2,1-2H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair