BDBM225953 FXR_43
SMILES: Fc1ccccc1S(=O)(=O)N1CCc2cc(C(=O)NCc3ccccc3)n(Cc3ccncc3)c2C1
InChI Key: InChIKey=WZHAJSAYRFJPAQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bile acid receptor (Homo sapiens (Human)) | BDBM225953 (FXR_43) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | D3R | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | n/a |
D3R | Assay Description The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [... | D3R 882: (2017) BindingDB Entry DOI: 10.7270/Q2MC8XWV | |||||||||||
More data for this Ligand-Target Pair |