BDBM226196 US9321790, 8

SMILES: CN(C)c1ccc(cn1)C(=O)CN1c2nc(cc(=O)n2C[C@@]1(C)C(F)(F)F)N1C[C@@H]2C[C@H]1CO2

InChI Key: InChIKey=VQXMDFARYBFRTQ-GXZWQRSESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 226196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110α/p85α (Homo sapiens (Human))	BDBM226196 (US9321790, 8) Show SMILES CN(C)c1ccc(cn1)C(=O)CN1c2nc(cc(=O)n2C[C@@]1(C)C(F)(F)F)N1C[C@@H]2C[C@H]1CO2 |TLB:15:27:32.33:30| Show InChI InChI=1S/C22H25F3N6O3/c1-21(22(23,24)25)12-30-19(33)7-18(29-9-15-6-14(29)11-34-15)27-20(30)31(21)10-16(32)13-4-5-17(26-8-13)28(2)3/h4-5,7-8,14-15H,6,9-12H2,1-3H3/t14-,15-,21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Sanofi US Patent					Assay Description The compounds according to the invention underwent pharmacological trials to measure the selectivity toward human lipid kinases and especially human ...				US Patent US9321790 (2016) BindingDB Entry DOI: 10.7270/Q2KD1WSG
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