BDBM22647 N-Me-pyrimidone deriv., 46::N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(morpholin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide
SMILES: Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C1COCCN1
InChI Key: InChIKey=FAQIGTGQCLFKIU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...) | BDBM22647 (N-Me-pyrimidone deriv., 46 | N-[(4-fluorophenyl)me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM-MRL | Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en... | J Med Chem 50: 4953-75 (2007) Article DOI: 10.1021/jm0704705 BindingDB Entry DOI: 10.7270/Q2BZ64BS | |||||||||||
More data for this Ligand-Target Pair |