BDBM22693 8-[(dimethylsulfamoyl)(methyl)amino]-N-[(4-fluorophenyl)methyl]-3-hydroxy-4-oxo-4H,6H,7H,8H-pyrrolo[1,2-a]pyrimidine-2-carboxamide::Bicyclic pyrimidinone, 22a

SMILES: CN(C)S(=O)(=O)N(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O

InChI Key: InChIKey=JSXPFHIXBFABPT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22693 (8-[(dimethylsulfamoyl)(methyl)amino]-N-[(4-fluorop...) Show SMILES CN(C)S(=O)(=O)N(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O Show InChI InChI=1S/C18H22FN5O5S/c1-22(2)30(28,29)23(3)13-8-9-24-16(13)21-14(15(25)18(24)27)17(26)20-10-11-4-6-12(19)7-5-11/h4-7,13,25H,8-10H2,1-3H3,(H,20,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 51: 861-74 (2008) Article DOI: 10.1021/jm701164t BindingDB Entry DOI: 10.7270/Q2765CNT
					More data for this Ligand-Target Pair