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SMILES: Cn1ccc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)n1

InChI Key: InChIKey=KFCSHAIHPNJEHP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227514   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK [360-635]


(Homo sapiens (Human))		BDBM227514
PNG
(US9334278, I-3)
Show SMILES Cn1ccc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)n1
Show InChI InChI=1S/C15H19N7O/c1-15(2,3)20-14(23)9-7-16-13-12(9)19-11(8-17-13)18-10-5-6-22(4)21-10/h5-8H,1-4H3,(H,16,17)(H,20,23)(H,18,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 21.1n/an/an/an/an/a30



Hoffmann-La Roche Inc.

US Patent


Assay Description
Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...

US Patent US9334278 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VN3
More data for this
Ligand-Target Pair