BDBM227532 US9334278, I-21

SMILES: CN(c1cccnc1)c1cnc2[nH]cc(C(=O)NC(C)(C)C)c2n1

InChI Key: InChIKey=MAFLUZXIYFUXOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SYK RPA purified, truncated construct of Spleen Tyrosine Kinase (aa 360-635) (Homo sapiens (Human))	BDBM227532 (US9334278, I-21) Show SMILES CN(c1cccnc1)c1cnc2[nH]cc(C(=O)NC(C)(C)C)c2n1 Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)12-9-19-15-14(12)21-13(10-20-15)23(4)11-6-5-7-18-8-11/h5-10H,1-4H3,(H,19,20)(H,22,24)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	30
Hoffmann-La Roche Inc. US Patent					Assay Description Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...				US Patent US9334278 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VN3
					More data for this Ligand-Target Pair