null

SMILES: CC(=O)N1CCC(COc2ncc(cn2)-c2cccc(COC(=O)NC(N)=N)c2F)CC1

InChI Key: InChIKey=CIQXENGVUDJJJL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM228069 (US9556160, ex 11) Show SMILES CC(=O)N1CCC(COc2ncc(cn2)-c2cccc(COC(=O)NC(N)=N)c2F)CC1 Show InChI InChI=1S/C21H25FN6O4/c1-13(29)28-7-5-14(6-8-28)11-31-20-25-9-16(10-26-20)17-4-2-3-15(18(17)22)12-32-21(30)27-19(23)24/h2-4,9-10,14H,5-8,11-12H2,1H3,(H4,23,24,27,30)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A rat VAP-1 enzyme (SSAO) (reference: Biol Pharm Bull. 2005 March; 28(3): 413-8) activity was measured by a radiochemistry-enzymatic assay using 14C-...				US Patent US9556160 (2017) BindingDB Entry DOI: 10.7270/Q2KP845Q
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM228069 (US9556160, ex 11) Show SMILES CC(=O)N1CCC(COc2ncc(cn2)-c2cccc(COC(=O)NC(N)=N)c2F)CC1 Show InChI InChI=1S/C21H25FN6O4/c1-13(29)28-7-5-14(6-8-28)11-31-20-25-9-16(10-26-20)17-4-2-3-15(18(17)22)12-32-21(30)27-19(23)24/h2-4,9-10,14H,5-8,11-12H2,1H3,(H4,23,24,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A human VAP-1 enzyme (SSAO) (reference: J Exp Med. 1998 Jul. 6; 188(1): 17 to 27) activity was measured by a radiochemistry-enzymatic assay using 14C...				US Patent US9556160 (2017) BindingDB Entry DOI: 10.7270/Q2KP845Q
					More data for this Ligand-Target Pair