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SMILES: CC1(C)CCC[NH+](CC2(CC2)NC(=O)c2ccc(cc2)-c2noc(n2)C(F)(F)F)C1

InChI Key: InChIKey=UWBSPFFYHKFGOE-UHFFFAOYSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228166   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))		BDBM228166
PNG
(US10047073, 8)
Show SMILES CC1(C)CCC[NH+](CC2(CC2)NC(=O)c2ccc(cc2)-c2noc(n2)C(F)(F)F)C1
Show InChI InChI=1S/C21H25F3N4O2/c1-19(2)8-3-11-28(12-19)13-20(9-10-20)26-17(29)15-6-4-14(5-7-15)16-25-18(30-27-16)21(22,23)24/h4-7H,3,8-13H2,1-2H3,(H,26,29)/p+1
PDB
MMDB

KEGG

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PC cid
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US Patent
n/an/a 30n/an/an/an/an/an/a



CHDI FOUNDATION, INC

US Patent


Assay Description
The Class I HDAC activity of Class IIa Histone Deacetylase (HDAC) inhibitors was quantified by measuring the cellular histone deacetylase enzymatic a...

US Patent US10047073 (2018)


BindingDB Entry DOI: 10.7270/Q2PG1TQC
More data for this
Ligand-Target Pair