BDBM228510 US9340521, E062

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2ccc(cc2)C2CCC2)c(Cl)c2CCCOc12

InChI Key: InChIKey=AZNJZHUZHCLPNI-TXKDOCKMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM228510 (US9340521, E062) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2ccc(cc2)C2CCC2)c(Cl)c2CCCOc12 |r| Show InChI InChI=1S/C26H31ClO6/c27-21-17(11-14-6-8-16(9-7-14)15-3-1-4-15)12-19(25-18(21)5-2-10-32-25)26-24(31)23(30)22(29)20(13-28)33-26/h6-9,12,15,20,22-24,26,28-31H,1-5,10-11,13H2/t20-,22-,23+,24-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	163	n/a	n/a	n/a	n/a	7.4	37
GREEN CROSS CORPORATION US Patent					Assay Description For sodium-dependent glucose transport assay, cells expressing hSGLT1 were seeded into a 96-well culture plate at a density of 5×104 cells/well...				US Patent US9340521 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60CH
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM228510 (US9340521, E062) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2ccc(cc2)C2CCC2)c(Cl)c2CCCOc12 |r| Show InChI InChI=1S/C26H31ClO6/c27-21-17(11-14-6-8-16(9-7-14)15-3-1-4-15)12-19(25-18(21)5-2-10-32-25)26-24(31)23(30)22(29)20(13-28)33-26/h6-9,12,15,20,22-24,26,28-31H,1-5,10-11,13H2/t20-,22-,23+,24-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	37
GREEN CROSS CORPORATION US Patent					Assay Description For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...				US Patent US9340521 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60CH
					More data for this Ligand-Target Pair