BDBM228800 NOEV::Sapienic acid (SpA)
SMILES: CCCCCCCCN[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
InChI Key: InChIKey=UPZUHYMBTUUPML-XGUBFFRZSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid-binding protein 5 (FABP5)(DSm) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 700 | -8.53 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University School of Medicine | Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... | J Biol Chem 289: 14941-54 (2014) Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Galactosidase (β-Gal)(R201C) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 940 | -8.55 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Galactosidase (β-Gal) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10E+3 | -8.45 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10E+3 | -8.26 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University School of Medicine | Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... | J Biol Chem 289: 14941-54 (2014) Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Galactosidase (β-Gal)(I51T) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.20E+3 | -8.40 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid-binding protein 5 (FABP5)(NLSm) (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.24E+3 | -8.19 | n/a | n/a | n/a | n/a | n/a | 8.2 | 30 |
Emory University School of Medicine | Assay Description In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini... | J Biol Chem 289: 14941-54 (2014) Article DOI: 10.1074/jbc.M113.514646 BindingDB Entry DOI: 10.7270/Q21835CT | |||||||||||
More data for this Ligand-Target Pair |